Martina Hieke

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

Meng S. Choy, Martina Hieke, Ganesan Senthil Kumar et al. · Proceedings of the National Academy of Sciences · 2014 · 133 citations · Full text

Molecular Regulation, Genetics, Retinoblastoma Protein +22

SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase

Martina Hieke, Carmen B. Rödl, Joanna Wiśniewska et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 56 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Design, Synthesis, and Biological Evaluation of a Novel Class of γ-Secretase Modulators with PPARγ Activity

Martina Hieke, Ramona Steri, Michaela Dittrich et al. · Journal of Medicinal Chemistry · 2010 · 36 citations · Full text

Discovery and Biological Evaluation of a Novel Class of Dual Microsomal Prostaglandin E₂Synthase-1/5-lipoxygenase Inhibitors Based on 2-[(4,6-Diphenethoxypyrimidin-2-yl)thio]hexanoic Acid

Martina Hieke, Christine Greiner, Michaela Dittrich et al. · Journal of Medicinal Chemistry · 2011 · 28 citations · Full text

Molecular Pharmacology, Pharmaceutical Science, Anti-inflammatory +13

A novel class of dual mPGES-1/5-LO inhibitors based on the α-naphthyl pirinixic acid scaffold

Martina Hieke, Christine Greiner, Theresa M. Thieme et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 18 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +12