Anna Hobler

Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

Alex D. Sheftel, Oliver Stehling, Antonio J. Pierik et al. · Proceedings of the National Academy of Sciences · 2010 · 389 citations · Full text

Mitochondrial Ferredoxins, Aldo-keto Reductase, Genetics +20

Human aldosterone synthase: Recombinant expression in E. coli and purification enables a detailed biochemical analysis of the protein on the molecular level

Anna Hobler, Norio Kagawa, Michael C. Hutter et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 41 citations

Biosynthesis, Molecular Physiology, Human Aldosterone Synthase +12

A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale

Lina Schiffer, Simone Brixius‐Anderko, Anna Hobler et al. · Microbial Cell Factories · 2015 · 35 citations · Full text

Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: Characterization of the products and their influence on mineralocorticoid receptor transactivation

Lina Schiffer, Anne-Rose Müller, Anna Hobler et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2016 · 14 citations

Human Cyp11b1, Adrenal Gland, Mineralocorticoid Receptor Transactivation +10