Chwan‐Deng Hsiao

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Jer-Yen Yang, Cong S. Zong, Weiya Xia et al. · Nature Cell Biology · 2008 · 693 citations · Full text

Mdm2-mediated Degradation, Medicine, Tumor Suppressor +4

SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2

Barrie Peck, Chun‐Yuan Chen, Ka-Kei Ho et al. · Molecular Cancer Therapeutics · 2010 · 430 citations

The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold

Zhijie Liu, Yuh‐Ju Sun, John P. Rose et al. · Nature Structural Biology · 1997 · 316 citations

Aldehyde Dehydrogenase Reveals, Aldehyde Dehydrogenase, Cellular Enzymology +10

Structure of the SARS Coronavirus Nucleocapsid Protein RNA-binding Dimerization Domain Suggests a Mechanism for Helical Packaging of Viral RNA

Chun-Yuan Chen, Chung‐ke Chang, Yi‐Wei Chang et al. · Journal of Molecular Biology · 2007 · 292 citations · Full text

Viral Rna, Virus Structure, Viral Replication +8

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification

Kuang‐Lei Tsai, Yun-chang Sun, Chih‐Yang Huang et al. · Nucleic Acids Research · 2007 · 193 citations · Full text

Crystal Structure, Molecular Biology, Transcriptional Regulation +16