Hubert Wyszkowski

Class-specific interactions between Sis1 J-domain protein and Hsp70 chaperone potentiate disaggregation of misfolded proteins

Hubert Wyszkowski, Anna Janta, Wiktoria Sztangierska et al. · Proceedings of the National Academy of Sciences · 2021 · 52 citations · Full text

Protein Assembly, Signal Recognition, Molecular Biology +20

Neutropenia and intellectual disability are hallmarks of biallelic and de novo CLPB deficiency

Saskia B. Wortmann, Szymon Ziętkiewicz, Sergio Guerrero‐Castillo et al. · Genetics in Medicine · 2021 · 37 citations · Full text

Genetic Disorder, Genetics, Inherited Metabolic Disease +7

Selective Hsp70-Dependent Docking of Hsp104 to Protein Aggregates Protects the Cell from the Toxicity of the Disaggregase

Tomasz Chamera, Agnieszka Kłosowska, Anna Janta et al. · Journal of Molecular Biology · 2019 · 22 citations

Protein Chemistry, Protein Function, Biochemistry +9

CLPB (caseinolytic peptidase B homolog), the first mitochondrial protein refoldase associated with human disease

Dagmara Mróz, Hubert Wyszkowski, Tomasz Szablewski et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2020 · 22 citations · Full text

Early steps of protein disaggregation by Hsp70 chaperone and class B J-domain proteins are shaped by Hsp110

Wiktoria Sztangierska, Hubert Wyszkowski, Maria Pokornowska et al. · eLife · 2024 · 13 citations · Full text