T. Manoharan

Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor

Lars Prade, Robert S. Huber, T. Manoharan et al. · Structure · 1997 · 71 citations · Full text

Class Pi Glutathione, Human Placenta, Biochemistry +5

Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase π

T. Manoharan, Andrew M. Gulick, Peter Reinemer et al. · Journal of Molecular Biology · 1992 · 59 citations

Crystal Structure, Biochemistry, Natural Sciences +8

Structural studies on human glutathione S-transferase pi. Substitution mutations to determine amino acids necessary for binding glutathione.

T. Manoharan, Andrew M. Gulick, Ralph B. Puchalski et al. · Journal of Biological Chemistry · 1992 · 55 citations · Full text

Pi Enzyme, Amino Acids, Biochemistry +13

Promoter-glutathione S-transferase Ya cDNA hybrid genes. Expression and conferred resistance to an alkylating molecule in mammalian cells.

T. Manoharan, Ralph B. Puchalski, Jeffrey A. Burgess et al. · Journal of Biological Chemistry · 1987 · 48 citations · Full text

Genetics, Gene Characterization, Molecular Genetics +16

Determination of a Binding Site for a Non‐Substrate Ligand in Mammalian Cytosolic Glutathione <i>S</i>‐Transferases by means of Fluorescence‐Resonance Energy Transfer

Nicolas Sluis‐Cremer, Nirinjini Naidoo, Warren Kaplan et al. · European Journal of Biochemistry · 1996 · 37 citations · Full text