Sarah Mackenzie

OTX015 (MK‐8628), a novel BET inhibitor, displays <i>in vitro</i> and <i>in vivo</i> antitumor effects alone and in combination with conventional therapies in glioblastoma models

Caroline Berenguer‐Daizé, Lucile Astorgues‐Xerri, Elodie Odore et al. · International Journal of Cancer · 2016 · 151 citations · Full text

Medicine, Oncology, Pharmacology +14

Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer

Gianluca Civenni, Roberto Bosotti, Andrea Timpanaro et al. · Cell Metabolism · 2019 · 102 citations · Full text

Medicine, Cell Biology, Oncology +17

Phase II Study of Oxaliplatin and Fluorouracil in Taxane- and Anthracycline-Pretreated Breast Cancer Patients

Laurent Zelek, Paul Cottu, M. Tubiana-Hulin et al. · Journal of Clinical Oncology · 2002 · 56 citations

Medicine, Oncology, Pharmacology +17

Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection

J.J. Maciag, Sarah Mackenzie, M.B. Tucker et al. · Proceedings of the National Academy of Sciences · 2016 · 54 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Phase I Safety and Pharmacodynamic of Inecalcitol, a Novel VDR Agonist with Docetaxel in Metastatic Castration-Resistant Prostate Cancer Patients

Jacques Médioni, G. Deplanque, Jean-­Marc Ferrero et al. · Clinical Cancer Research · 2014 · 43 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17