Guanhui Wu

A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription

Buket Onel, Megan Carver, Guanhui Wu et al. · Journal of the American Chemical Society · 2016 · 122 citations · Full text

Transcriptional Regulation, Dynamic Equilibrium, Bcl2 Gene +14

DDX5 helicase resolves G-quadruplex and is involved in <i>MYC</i> gene transcriptional activation

Guanhui Wu, Zheng Xing, Elizabeth Tran et al. · Proceedings of the National Academy of Sciences · 2019 · 121 citations · Full text

Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the <i>MYC</i> Promoter G-Quadruplex and Downregulate <i>MYC</i>

Kai‐Bo Wang, Mohamed Elsayed, Guanhui Wu et al. · Journal of the American Chemical Society · 2019 · 105 citations · Full text

Molecular Recognition of the Hybrid‐2 Human Telomeric G‐Quadruplex by Epiberberine: Insights into Conversion of Telomeric G‐Quadruplex Structures

Clement Lin, Guanhui Wu, Kai‐Bo Wang et al. · Angewandte Chemie International Edition · 2018 · 92 citations

The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression

Robert V. Brown, Ting Wang, Venkateshwar Reddy Chappeta et al. · Journal of the American Chemical Society · 2017 · 90 citations

Acute Lung Injury, Unexpected Effects, Molecular Regulation +25