Kenji Takenuki

Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives

Akira Matsuda, Kenji Takenuki, Motohiro Tanaka et al. · Journal of Medicinal Chemistry · 1991 · 86 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Nucleosides and nucleotides. 83. Design, synthesis, and antineoplastic activity of 2'-deoxy-2'-methylidenecytidine

Kenji Takenuki, Akira Matsuda, Takuma Sasaki et al. · Journal of Medicinal Chemistry · 1988 · 74 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Alkyl addition reaction of pyrimidine 2'-ketonucleosides: Synthesis of 2'-branched-chain sugar pyrimidine nucleosides. Nucleodides and nucleotides. LXXXI.

Akira Matsuda, Hiroko Itoh, Kenji Takenuki et al. · Chemical and Pharmaceutical Bulletin · 1988 · 61 citations · Full text

Natural Sciences, Biochemistry, Chemistry +14

Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl)pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleoside

Akira Matsuda, Kenji Takenuki · Journal of Medicinal Chemistry · 1991 · 48 citations

Pharmacy, Biochemistry, Chemistry +15

Radical deoxygenation of tert-alcohols in 2'-branched-chain sugar pyrimidine nucleosides: Synthesis and antileukemic activity of 2'-deoxy-2'(S)-methylcytidine.

Akira Matsuda, Kenji Takenuki, Hiroko Itoh et al. · Chemical and Pharmaceutical Bulletin · 1987 · 36 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13