Takeshi Shimizudani

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

Shinsuke Nakagawa, Mária A. Deli, Hiroko Kawaguchi et al. · Neurochemistry International · 2008 · 735 citations · Full text

Medicine, Neurobiology, Neuroscience +12

Stereoselective Glucuronidation of Propranolol in Human and Cynomolgus Monkey Liver Microsomes: Role of Human Hepatic UDP-Glucuronosyltransferase Isoforms, UGT1A9, UGT2B4 and UGT2B7

Nobumitsu Hanioka, Keiko Hayashi, Takeshi Shimizudani et al. · Pharmacology · 2008 · 24 citations

Medicine, Biochemistry, Pharmacology +16

Novel Carbapenem Antibiotics for Parenteral and Oral Applications: <i>In Vitro</i> and <i>In Vivo</i> Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Koichi Fujimoto, Koji Takemoto, Kazuo Hatano et al. · Antimicrobial Agents and Chemotherapy · 2012 · 18 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +16

Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19

Shizuo Narimatsu, Toshiyuki Nakata, Takeshi Shimizudani et al. · Chemico-Biological Interactions · 2010 · 17 citations

Medicine, Pharmacokinetics, Pharmacology +15

Experimental verification of the efficacy of optimized two-step infusion therapy with meropenem using an in vitro pharmacodynamic model and Monte Carlo simulation

Ken Eguchi, Katsunori Kanazawa, Takeshi Shimizudani et al. · Journal of Infection and Chemotherapy · 2010 · 17 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +10