Mitchell S. Wang

DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

Marian C. Okondo, Darren C. Johnson, Ramya Sridharan et al. · Nature Chemical Biology · 2016 · 300 citations · Full text

Inflammation, Signal Transduction, Apoptosis +9

Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells

Fella Tamzalit, Mitchell S. Wang, Weiyang Jin et al. · Science Immunology · 2019 · 130 citations · Full text

Engineering, Cell Adhesion, Apoptosis +22

Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity

Mitchell S. Wang, Yuesong Hu, Elisa E. Sanchez et al. · Nature Communications · 2022 · 74 citations · Full text

Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity

Miguel de Jesus, Alexander Settle, Daan Vorselen et al. · Science Immunology · 2024 · 26 citations · Full text

Engineering, Immunology, Single-cell Topographical Profiling +23

Modulating T Cell Activation Using Depth Sensing Topographic Cues

Parthiv Kant Chaudhuri, Mitchell S. Wang, Charles T. Black et al. · Advanced Biosystems · 2020 · 14 citations · Full text