Jorge Rodríguez

Decreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis

Lawrence J. Hayward, Jorge Rodríguez, Ji Won Kim et al. · Journal of Biological Chemistry · 2002 · 385 citations · Full text

Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS

Jennifer Stine Elam, Alexander B. Taylor, Richard W. Strange et al. · Nature Structural & Molecular Biology · 2003 · 316 citations

Neurodegenerative Diseases, Water-filled Nanotubes, Amyotrophic Lateral Sclerosis +10

The Structure of Holo and Metal-deficient Wild-type Human Cu, Zn Superoxide Dismutase and its Relevance to Familial Amyotrophic Lateral Sclerosis

Richard W. Strange, S.V. Antonyuk, Michael A. Hough et al. · Journal of Molecular Biology · 2003 · 255 citations

Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Biochemistry +11

Dimer destabilization in superoxide dismutase may result in disease-causing properties: Structures of motor neuron disease mutants

Michael A. Hough, J. Günter Grossmann, S.V. Antonyuk et al. · Proceedings of the National Academy of Sciences · 2004 · 242 citations · Full text

Familial Amyotrophic Lateral Sclerosis-associated Mutations Decrease the Thermal Stability of Distinctly Metallated Species of Human Copper/Zinc Superoxide Dismutase

Jorge Rodríguez, Joan Selverstone Valentine, Daryl K. Eggers et al. · Journal of Biological Chemistry · 2002 · 237 citations · Full text

Altered Thermal Stability, Amyotrophic Lateral Sclerosis, Biochemistry +14