Ann Greer

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR

Joan M. Carboni, Mark D. Wittman, Zheng Yang et al. · Molecular Cancer Therapeutics · 2009 · 278 citations · Full text

Small Molecule Inhibitor, Cancer Biology, Insulin Signaling +16

Tumor Development by Transgenic Expression of a Constitutively Active Insulin-Like Growth Factor I Receptor

Joan M. Carboni, Adrian V. Lee, Darryl L. Hadsell et al. · Cancer Research · 2005 · 203 citations · Full text

Receptor Antagonists, Cell Proliferation, Tumor Biology +16

The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors

Fei Huang, Ann Greer, Warren Hurlburt et al. · Cancer Research · 2008 · 163 citations · Full text

Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Mark D. Wittman, Joan M. Carboni, Ricardo M. Attar et al. · Journal of Medicinal Chemistry · 2005 · 134 citations · Full text

Pharmacotherapy, Insulin Receptor, Insulin Signaling +21

Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model

Fei Huang, Warren Hurlburt, Ann Greer et al. · Cancer Research · 2010 · 115 citations · Full text