Takao Shishido

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

Frederick G. Hayden, Norio Sugaya, Nobuo Hirotsu et al. · New England Journal of Medicine · 2018 · 929 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +14

Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil

Shinya Omoto, Valentina Speranzini, Takashi Hashimoto et al. · Scientific Reports · 2018 · 436 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +16

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

Takeshi Noshi, Mitsutaka Kitano, K. Taniguchi et al. · Antiviral Research · 2018 · 376 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Early treatment with baloxavir marboxil in high-risk adolescent and adult outpatients with uncomplicated influenza (CAPSTONE-2): a randomised, placebo-controlled, phase 3 trial

Michael G. Ison, Simon Portsmouth, Yuki Yoshida et al. · The Lancet Infectious Diseases · 2020 · 262 citations

Pharmacy, Pediatrics, Pharmacotherapy +6

Treatment-Emergent Influenza Variant Viruses With Reduced Baloxavir Susceptibility: Impact on Clinical and Virologic Outcomes in Uncomplicated Influenza

Takeki Uehara, Frederick G. Hayden, Keiko Kawaguchi et al. · The Journal of Infectious Diseases · 2019 · 192 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacotherapy +16