L. M. Flynn

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.

Robert V. Farese, S L Ruland, L. M. Flynn et al. · Proceedings of the National Academy of Sciences · 1995 · 265 citations

Life Sciences, Genetics, Molecular Genetics +16

Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes

Martin Raabe, L. M. Flynn, Constance Zlot et al. · Proceedings of the National Academy of Sciences · 1998 · 260 citations

Life Sciences, Biochemistry, Molecular Genetics +17

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

D A Purcell-Huynh, Robert V. Farese, David Johnson et al. · Journal of Clinical Investigation · 1995 · 197 citations · Full text

Life Sciences, Biochemistry, Cardiology +16

Phenotypic analysis of mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

Robert V. Farese, Murielle M. Véniant, C M Cham et al. · Proceedings of the National Academy of Sciences · 1996 · 141 citations

Life Sciences, Developmental Biology, Genetics +13

Genes for Apolipoprotein B and Microsomal Triglyceride Transfer Protein Are Expressed in the Heart

Lars B. Nielsen, Murielle M. Véniant, Jan Borén et al. · Circulation · 1998 · 132 citations · Full text

Life Sciences, Genetics, Molecular Biology +15