Andrew P. Montgomery

Transition state-based ST6Gal I inhibitors: Mimicking the phosphodiester linkage with a triazole or carbamate through an enthalpy-entropy compensation

Andrew P. Montgomery, Danielle Skropeta, Haibo Yu · Scientific Reports · 2017 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Fragment-based drug discovery for disorders of the central nervous system: designing better drugs piece by piece

Bill W. G. L. Chan, Nicholas B. Lynch, Wendy Tran et al. · Frontiers in Chemistry · 2024 · 24 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

DYRK1A Negatively Regulates CDK5-SOX2 Pathway and Self-Renewal of Glioblastoma Stem Cells

Brianna Chen, Dylan McCuaig-Walton, Sean Jing Xiang Tan et al. · International Journal of Molecular Sciences · 2021 · 23 citations · Full text

Medicine, Cell Biology, Oncology +17

Computational characterisation of the interactions between human ST6Gal I and transition-state analogue inhibitors: insights for inhibitor design

Andrew P. Montgomery, Rémi Szabo, Danielle Skropeta et al. · Journal of Molecular Recognition · 2015 · 19 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Design, synthesis and evaluation of carbamate-linked uridyl-based inhibitors of human ST6Gal I

Andrew P. Montgomery, Christopher Dobie, Rémi Szabo et al. · Bioorganic & Medicinal Chemistry · 2020 · 18 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12