Laura A. Bruins

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi et al. · Blood · 2011 · 602 citations · Full text

Medicine, Oncology, Pharmacology +9

Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes

K. Martin Kortüm, Nur Hafzan Md Hanafiah, Chang-Xi Shi et al. · Blood · 2016 · 256 citations · Full text

Medicine, Molecular Genetics, Oncology +14

Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma

Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi et al. · Blood · 2014 · 214 citations · Full text

Life Sciences, Molecular Biology, Oncology +11

The clinical significance of cereblon expression in multiple myeloma

Steven R. Schuster, K. Martin Kortuem, Yuan Xiao Zhu et al. · Leukemia Research · 2013 · 109 citations · Full text

Medicine, Hematology, Oncology +16

RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5

Yuan Xiao Zhu, Rodger E. Tiedemann, Chang-Xin Shi et al. · Blood · 2011 · 105 citations · Full text

Medicine, Molecular Biology, Oncology +11