Top-Down Quantitative Proteomics Identified Phosphorylation of Cardiac Troponin I as a Candidate Biomarker for Chronic Heart Failure

Jiang Zhang, Moltu J. Guy, Holly S. Norman, +9

Journal of Proteome Research

Heart FailureEngineeringCandidate BiomarkerCandidate BiomarkersCardiovascular Translational Research +21

Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state

Ying Ge, Inna N. Rybakova, Qingge Xu, +1

Proceedings of the National Academy of Sciences

Cardiac MuscleMolecular BiologyCytoskeletonCellular PhysiologyProteomics +18

Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3

Michael G. Johnson, An‐Rong Li, Jiwen Liu, +19

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineNatural Sciences +6

PP2A-B′ holoenzyme substrate recognition, regulation and role in cytokinesis

Cheng-Guo Wu, Hui Chen, Feng Guo, +18

Cell Discovery

Transcriptional RegulationProtein FunctionSignal TransductionSignaling PathwayMolecular Pathway +13

Mesoporous zirconium oxide nanomaterials effectively enrich phosphopeptides for mass spectrometry-based phosphoproteomics

Cory A. Nelson, Jeannine R. Szczech, Qingge Xu, +3

Chemical Communications

Chemical EngineeringEngineeringNanomaterialsNanotechnologyPeptide Engineering +11

Effective Enrichment and Mass Spectrometry Analysis of Phosphopeptides Using Mesoporous Metal Oxide Nanomaterials

Cory A. Nelson, Jeannine R. Szczech, Chad J. Dooley, +5

Analytical Chemistry

Comprehensive characterization of monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry

Yutong Jin, Ziqing Lin, Qingge Xu, +5

mAbs

ImmunologyBiological Mass SpectrometryPathologyImmunophenotypingComprehensive Characterization +16

Top-down Targeted Proteomics for Deep Sequencing of Tropomyosin Isoforms

Ying Peng, Xin Chen, Han Zhang, +3

Journal of Proteome Research

Biological Mass SpectrometryMolecular BiologyCytoskeletonCellular PhysiologyProteomic Technology +21

Stereocontrolled Total Synthesis of Alkaloid G via the Oxy-anion Cope Rearrangement and Improved Total Synthesis of (+)-Ajmaline

Tao Wang, Qingge Xu, Yu Peng, +2

Organic Letters

Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation

Bifan Chen, Ziqing Lin, Yanlong Zhu, +8

Analytical Chemistry

Immunocytochemical TechniqueBiological Mass SpectrometryPeptide ScienceAnalytical UltracentrifugationChemical Biology +24