MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Roland Kolbeck, Alexander Kozhich, Masamichi Koike, +17

Journal of Allergy and Clinical Immunology

ImmunotherapyMedicineImmunologyCell DeathImmunologic Mechanism +3

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

Michel Laviolette, David Gossage, Gail M. Gauvreau, +9

Journal of Allergy and Clinical Immunology

AsthmaAllergyRespiratory DiseasesImmunologySputum Eosinophilia +6

Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study

Mario Castro, Sally E. Wenzel, Eugene R. Bleecker, +12

The Lancet Respiratory Medicine

AsthmaRheumatologyAllergyAllergy MedicinePhase 2B +8

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma

William W. Busse, Rohit Katial, David Gossage, +9

Journal of Allergy and Clinical Immunology

AsthmaBiologic ActivityMild AsthmaClinical AllergyMedicine +6

High Blood Eosinophil Count Is a Risk Factor for Future Asthma Exacerbations in Adult Persistent Asthma

Robert S. Zeiger, Michael Schatz, Qiaowu Li, +4

The Journal of Allergy and Clinical Immunology In Practice

AsthmaAllergyFuture Asthma ExacerbationsImmunologyRisk Factor +4

Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): two randomised double-blind, placebo-controlled phase 3 trials

Alan F. Barker, Anne E. O’Donnell, Patrick A. Flume, +15

The Lancet Respiratory Medicine

Non-cystic Fibrosis BronchiectasisAllergyPlacebo-controlled Phase 3Advanced Lung DiseaseInhalation Solution +4

High blood eosinophil count is associated with more frequent asthma attacks in asthma patients

Trung N. Tran, Deepak Khatry, Xiongkan Ke, +2

Annals of Allergy Asthma & Immunology

AsthmaAllergyInflammatory Lung DiseaseImmunologyFrequent Asthma Attacks +4

Pretranslational regulation of type I collagen, fibronectin, and a 50-kilodalton noncollagenous extracellular protein by dexamethasone in rat fibroblasts.

Rajendra Raghow, David Gossage, A H Kang

Journal of Biological Chemistry

Cell CultureCell ProliferationCytoskeletonFunctional MrnasCellular Physiology +16

A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell Transplant Recipients

Roy F. Chemaly, Sanjeet Dadwal, Anne Bergeron, +27

Clinical Infectious Diseases

Transcriptional regulation of type I collagen genes in cultured fibroblasts by a factor isolated from thioacetamide-induced fibrotic rat liver.

Rajendra Raghow, David Gossage, Jerome M. Seyer, +1

Journal of Biological Chemistry