David Gossage

MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Roland Kolbeck, Alexander Kozhich, Masamichi Koike et al. · Journal of Allergy and Clinical Immunology · 2010 · 578 citations · Full text

Pharmacy, Immunology, Antibody Engineering +8

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

Michel Laviolette, David Gossage, Gail M. Gauvreau et al. · Journal of Allergy and Clinical Immunology · 2013 · 508 citations

Medicine, Immunology, Pharmacotherapy +16

Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study

Mario Castro, Sally E. Wenzel, Eugene R. Bleecker et al. · The Lancet Respiratory Medicine · 2014 · 484 citations

Life Sciences, Immunology, Pharmacology +16

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma

William W. Busse, Rohit Katial, David Gossage et al. · Journal of Allergy and Clinical Immunology · 2010 · 278 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

High Blood Eosinophil Count Is a Risk Factor for Future Asthma Exacerbations in Adult Persistent Asthma

Robert S. Zeiger, Michael Schatz, Qiaowu Li et al. · The Journal of Allergy and Clinical Immunology In Practice · 2014 · 247 citations

Medicine, Immunology, Internal Medicine +14