Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

Yu Chen, Ceyang Su, Min Ke, +10

PLoS Pathogens

Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide <i>In Vitro</i> and <i>In Vivo</i> To Reduce Replication and Pathogenesis

Yi Wang, Andong Wu, Shan Xu, +8

Journal of Virology

Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase

Yu Chen, Jiali Tao, Andong Wu, +7

Journal of Virology

Virus StructureViral ReplicationBiochemistryNatural SciencesStructure-function Analysis +13

Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2′-O-methyltransferase activity of nsp10/nsp16 complex

Min Ke, Yu Chen, Andong Wu, +8

Virus Research

Virus StructureMedicineViral PathogenesisNsp10/nsp16 ComplexMolecular Biology +6

Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP

Jin Xu, Yu Chen, Cong Zeng, +7

Virus Research

Guanine-n7 Methyltransferase ActivityNucleotide GtpBiochemistryNatural SciencesMolecular Biology +6

Prediction and biochemical analysis of putative cleavage sites of the 3C-like protease of Middle East respiratory syndrome coronavirus

Andong Wu, Yi Wang, Cong Zeng, +6

Virus Research

3C-like ProteasePutative Cleavage SitesVirus StructureMolecular VirologyViral Replication +9

Hepatitis B Virus Polymerase Suppresses NF-κB Signaling by Inhibiting the Activity of IKKs via Interaction with Hsp90β

Dan Liu, Andong Wu, Lei Cui, +4

PLoS ONE

Yeast-based assays for the high-throughput screening of inhibitors of coronavirus RNA cap guanine-N7-methyltransferase

Zidao Wang, Jiali Tao, Yi Wang, +6

Antiviral Research

Viral DiagnosticsAntiviral Drug DevelopmentAntiviral TherapyMolecular BiologyVirology +8

Identification and Characterization of a Ribose 2′- <i>O</i> -Methyltransferase Encoded by the Ronivirus Branch of Nidovirales

Cong Zeng, Andong Wu, Yi Wang, +11

Journal of Virology

SfDredd, a Novel Initiator Caspase Possessing Activity on Effector Caspase Substrates in Spodoptera frugiperda

Zhouning Yang, Ke Zhou, Hao Liu, +3

PLoS ONE

Bioorganic ChemistryApoptosisSpodoptera FrugiperdaMolecular BiologyCell Death +16