Panagiota Roumelioti

An Effort To Understand the Molecular Basis of Hypertension through the Study of Conformational Analysis of Losartan and Sarmesin Using a Combination of Nuclear Magnetic Resonance Spectroscopy and Theoretical Calculations

Thomas Mavromoustakos, Antonios Kolocouris, María Zervoú et al. · Journal of Medicinal Chemistry · 1999 · 121 citations

The design and synthesis of a potent angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone angiotensin II

John Matsoukas, Ludmila Polevaya, Juris Ancans et al. · Bioorganic & Medicinal Chemistry · 2000 · 44 citations

Medicinal Chemistry, Hormone Angiotensin Ii, G Protein-coupled Receptor +9

Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of π*–π* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT1 non-peptide antagonists

Ludmila Polevaya, Thomas Mavromoustakos, Panagiotis Zoumboulakis et al. · Bioorganic & Medicinal Chemistry · 2001 · 36 citations

Molecular Pharmacology, Biochemistry, Medicine +8

An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT1 Angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies

George Agelis, Panagiota Roumelioti, Amalia Resvani et al. · Journal of Computer-Aided Molecular Design · 2010 · 21 citations

Medicinal Chemistry, Biochemistry, Medicine +9

Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-Chain bridges

Panagiota Roumelioti, Ludmila Polevaya, Panagiotis Zoumpoulakis et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 21 citations

Combinatorial Chemistry, Side-chain Bridges, Medicinal Chemistry +8