Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study

Philip J. O’Connell, Weijia Zhang, Madhav C. Menon, +23

The Lancet

Translational MedicineUrologyTransplantationKidney TransplantKidney Research +13

DNA methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology

Mihaela Stefan, Weijia Zhang, Erlinda Concepcion, +2

Journal of Autoimmunity

ChromatinType 1Genetic DeterminantGenetic DisorderEpigenetic Change +10

The Role of Macrophages in the Development of Human Renal Allograft Fibrosis in the First Year After Transplantation

Daisuke Toki, Wei Zhang, K. Hor, +8

American Journal of Transplantation

Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression

Ying Fan, Zhengzi Yi, Vivette D. D’Agati, +11

Diabetes

Glomerular DiseaseDisease ProgressionAdvanced Dn KidneysImmunologyPathology +17

Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells

Kerstin Ebefors, Robert J. Wiener, Liping Yu, +8

Kidney International

A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection

Weijia Zhang, Zhengzi Yi, Karen Keung, +25

Journal of the American Society of Nephrology

HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy

Man Chen, Madhav C. Menon, Wenlin Wang, +15

Nature Communications

Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis

Madhav C. Menon, Peter Y. Chuang, Zhengzhe Li, +22

Journal of Clinical Investigation

Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions

Zuchra Zakirova, Tomas Fanutza, Justine Bonet, +9

PLoS Genetics

Molecular RegulationGeneticsInvoluntary Muscle ContractionsNeurotransmissionDystonia Genes +22

Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth

Chunyan Ren, Guangtao Zhang, Fangbin Han, +17

Proceedings of the National Academy of Sciences