Robert M. Tombes

Metabolite channeling: A phosphorylcreatine shuttle to mediate high energy phosphate transport between sperm mitochondrion and tail

Robert M. Tombes, Bennett M. Shapiro · Cell · 1985 · 250 citations

Biochemistry, Bioenergetics, Membrane Transport +14

An adhesion-associated agonist from the zona pellucida activates G protein-promoted elevations of internal Ca2+ and pH that mediate mammalian sperm acrosomal exocytosis

Harvey M. Florman, Robert M. Tombes, Neal L. First et al. · Developmental Biology · 1989 · 238 citations

Internal Ca2+, Oocyte, Infertility +12

Dietary fibers: V. Binding of bile salts, phospholipids and cholesterol from mixed micelles by bile acid sequestrants and dietary fibers

George V. Vahouny, Robert M. Tombes, Marie M. Cassidy et al. · Lipids · 1980 · 193 citations

The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic

Robert M. Tombes, L. Kelly AUER, Ross B. Mikkelsen et al. · Biochemical Journal · 1998 · 187 citations · Full text

Cell Death, Cell Cycle, Cellular Physiology +17

G1 cell cycle arrest and apoptosis are induced in NIH 3T3 cells by KN-93, an inhibitor of CaMK-II (the multifunctional Ca2+/CaM kinase).

Robert M. Tombes, Stephen R. Grant, Eric H. Westin et al. · PubMed · 1995 · 122 citations

Apoptosis, Immunology, Kn-93 Release +19