Blanca Segura‐Pacheco

Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.

Blanca Segura‐Pacheco, Catalina Trejo‐Becerril, Enrique Pérez‐Cárdenas et al. · PubMed · 2003 · 206 citations

Medicine, Oncology, Pharmacology +17

A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

Pilar Zambrano, Blanca Segura‐Pacheco, Enrique Pérez‐Cárdenas et al. · BMC Cancer · 2005 · 150 citations · Full text

Medicine, Oncology, Pharmacology +17

Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines

Alma Chávez‐Blanco, Carlos Pérez‐Plasencia, Enrique Pérez‐Cárdenas et al. · Cancer Cell International · 2006 · 142 citations · Full text

Medicine, Oncology, Pharmacology +15

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

Alma Chávez‐Blanco, Blanca Segura‐Pacheco, Enrique Pérez‐Cárdenas et al. · Molecular Cancer · 2005 · 128 citations · Full text

Medicine, Oncology, Pharmacology +17

Hydralazine target: From blood vessels to the epigenome

Claudia Arce, Blanca Segura‐Pacheco, Enrique Pérez‐Cárdenas et al. · Journal of Translational Medicine · 2006 · 119 citations · Full text

Medicine, Oncology, Pharmacology +16