Brian L. Trippe

De novo design of protein structure and function with RFdiffusion

Joseph L. Watson, David Juergens, Nathaniel R. Bennett et al. · Nature · 2023 · 2K citations · Full text

Engineering, Bioinformatics, Biology +15

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

E. Weeks, Jacob C. Ulirsch, Nathan Cheng et al. · Nature Genetics · 2023 · 301 citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models

Joseph L. Watson, David Juergens, Nathaniel R. Bennett et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 148 citations · Full text

Life Sciences, Bioinformatics, Computational Biology +15

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

E. Weeks, Jacob C. Ulirsch, Nathan Cheng et al. · medRxiv · 2020 · 132 citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Diffusion probabilistic modeling of protein backbones in 3D for the motif-scaffolding problem

Brian L. Trippe, Jason Yim, Doug Tischer et al. · arXiv (Cornell University) · 2022 · 96 citations · Full text

Engineering, Bioinformatics, Computational Biology +14