MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents

Martín Monte, Marta Simonatto, Leticia Y. Peche, +5

Proceedings of the National Academy of Sciences

Mage-a Tumor AntigensCancer BiologyTumor BiologyOncologyCancer Cell Biology +14

Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers

Iros Barozzi, Marta Simonatto, Silvia Bonifacio, +4

Molecular Cell

ChromatinTranscriptional RegulationSystems BiologyDna FeaturesChromatin Remodeling +10

Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk

Viviana Piccolo, Alessia Curina, Marco Genua, +6

Nature Immunology

Macrophage Polarization ProgramsFunctional GenomicsEpigenetic RegulationMedicineNatural Sciences +8

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination

Liv Austenaa, Iros Barozzi, Marta Simonatto, +13

Molecular Cell

Transcriptional RegulationMolecular RegulationMedicineGeneticsEnforced Early Termination +8

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels

Alessia Peserico, Fulvio Chiacchiera, Valentina Grossi, +10

Cellular and Molecular Life Sciences

Molecular PhysiologySignal TransductionMitochondrial FunctionBiochemistryPhysiology +6

High constitutive activity of a broad panel of housekeeping and tissue-specific <i>cis</i>-regulatory elements depends on a subset of ETS proteins

Alessia Curina, Alberto Termanini, Iros Barozzi, +9

Genes & Development

Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models

Fulvio Chiacchiera, Valentina Grossi, Marianna Cappellari, +8

Cancer Letters

Colorectal Cancer GrowthP38/erk CrosstalkChemoprevention StrategyMedicineApoptosis +10

Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells

Federico Comoglio, Marta Simonatto, Sara Polletti, +4

Genes & Development

H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats

Francesco Gualdrini, Sara Polletti, Marta Simonatto, +3

Genes & Development

Histone ModificationsEpigenetic ChangeGeneticsMolecular BiologyEpigenetics +21

DNA damage-activated ABL-MyoD signaling contributes to DNA repair in skeletal myoblasts

Marta Simonatto, Fabrizia Marullo, Fulvio Chiacchiera, +4

Cell Death and Differentiation

ChromatinGenome InstabilitySkeletal MyoblastsDna DamageBone Morphogenic Protein +5