Rafael M. Costa

Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy

Larissa B. Teixeira, Lucas T. Parreiras‐e‐Silva, Thiago Bruder‐Nascimento et al. · Scientific Reports · 2017 · 105 citations · Full text

TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice

Rafael M. Costa, Karla B Neves, Fabíola Mestriner et al. · Cardiovascular Diabetology · 2016 · 97 citations · Full text

Increased mitochondrial ROS generation mediates the loss of the anti‐contractile effects of perivascular adipose tissue in high‐fat diet obese mice

Rafael M. Costa, Rafael Sobrano Fais, Carlos Roberto Porto Dechandt et al. · British Journal of Pharmacology · 2016 · 84 citations · Full text

Conjugation of Human Topoisomerase 2α with Small Ubiquitin-like Modifiers 2/3 in Response to Topoisomerase Inhibitors: Cell Cycle Stage and Chromosome Domain Specificity

Marta Agostinho, Vera Lúcia Pereira dos Santos, Fernando Ferreira et al. · Cancer Research · 2008 · 62 citations · Full text

H2O2 generated from mitochondrial electron transport chain in thoracic perivascular adipose tissue is crucial for modulation of vascular smooth muscle contraction

Rafael M. Costa, Fernando Filgueira, Rita C. Tostes et al. · Vascular Pharmacology · 2016 · 54 citations · Full text