Chromosomal instability drives metastasis through a cytosolic DNA response

Samuel F. Bakhoum, Bryan Ngo, Ashley M. Laughney, +30

Nature

ChromatinGenome InstabilityChromosomal InstabilityChromosomal RearrangementMedicine +1

Nuclear Deformation Causes DNA Damage by Increasing Replication Stress

Pragya Shah, Chad M. Hobson, Svea Cheng, +4

Current Biology

ChromatinGenome InstabilityDna DamageChromatin RemodelingNatural Sciences +6

Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

Emily Bell, Pragya Shah, Noam Zuela-Sopilniak, +13

Oncogene

Breast OncologyMetastatic CapacityMedicineCell-matrix InteractionCell Migration +7

Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

Sachi Horibata, Katherine E. Rogers, David Sadegh, +5

BMC Cancer

Hydroxyapatite mineral enhances malignant potential in a tissue-engineered model of ductal carcinoma in situ (DCIS)

Frank He, Nora L. Springer, Matthew A. Whitman, +15

Biomaterials

Tumor BiologyMalignant DiseaseHydroxyapatiteTissue-engineered ModelBioceramic +8

ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels

Pragya Shah, Connor W. McGuigan, Svea Cheng, +4

Frontiers in Cell and Developmental Biology

Nuclear deformation causes DNA damage by increasing replication stress

Pragya Shah, Chad M. Hobson, Svea Cheng, +4

Dna DamageGeneticsMolecular BiologyCell CycleSummary Cancer Metastasis +17

<scp>PP2A</scp> methylesterase <scp>PME</scp> ‐1 suppresses anoikis and is associated with therapy relapse of <scp> <i>PTEN</i> </scp> ‐deficient prostate cancers

Anna Aakula, Aleksi Isomursu, Christian Rupp, +16

Molecular Oncology

Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

Emily Bell, Pragya Shah, Noam Zuela-Sopilniak, +13