Marie‐Christine Haaz

Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions.

Marie‐Christine Haaz, Laurent P. Rivory, C. Riché et al. · PubMed · 1998 · 159 citations

Chemoprevention Strategy, Human Hepatic Microsomes, Toxicological Mechanism +17

Pharmacokinetic interrelationships of irinotecan (CPT-11) and its three major plasma metabolites in patients enrolled in phase I/II trials.

Laurent P. Rivory, Marie‐Christine Haaz, Pierre Canal et al. · PubMed · 1997 · 140 citations

Plasma Kinetics, Chemoprevention Strategy, Pharmacokinetic Interrelationships +18

Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients.

Laurent P. Rivory, Jean‐François Riou, Marie‐Christine Haaz et al. · PubMed · 1996 · 133 citations

Pharmaceutical Science, Pharmacotherapy, Major Plasma Metabolite +16

Identification of a New Metabolite of CPT-11 (Irinotecan): Pharmacological Properties and Activation to SN-38

Helen M. Dodds, Marie‐Christine Haaz, Jean‐François Riou et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 113 citations

Molecular Determinants of the Cytotoxicity of Platinum Compounds

Antoine Vekris, Delphine Meynard, Marie‐Christine Haaz et al. · Cancer Research · 2004 · 81 citations · Full text

Chemoprevention Strategy, Gene Expression Profiling, Tumor Biology +17