Colleen E. Keohane

A new class of synthetic retinoid antibiotics effective against bacterial persisters

Wooseong Kim, Wenpeng Zhu, Gabriel L. Hendricks et al. · Nature · 2018 · 394 citations

Bacterial Persisters, Health Sciences, Antibiotics +14

Promysalin Elicits Species-Selective Inhibition of <i>Pseudomonas aeruginosa</i> by Targeting Succinate Dehydrogenase

Colleen E. Keohane, A. Duncan Steele, Christian Fetzer et al. · Journal of the American Chemical Society · 2018 · 91 citations · Full text

Succinate Dehydrogenase, Antimicrobial Drug Discovery, Biosynthesis +13

Total Synthesis and Biological Investigation of (−)-Promysalin

A. Duncan Steele, Kyle W. Knouse, Colleen E. Keohane et al. · Journal of the American Chemical Society · 2015 · 38 citations

Bioorganic Chemistry, Antibiotic Adjuvant, Antimicrobial Chemotherapy +18

Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity

A. Duncan Steele, Colleen E. Keohane, Kyle W. Knouse et al. · Journal of the American Chemical Society · 2016 · 31 citations

Biosynthesis, Bioorganic Chemistry, Unique Bioactivity +14

The Rhizosphere Microbiome: A Playground for Natural Product Chemists

William M. Wuest, Colleen E. Keohane, A. Duncan Steele · Synlett · 2015 · 16 citations

Microbial Diversity, Rhizosphere Microbiome, Bioorganic Chemistry +14