Hiromitsu Shinohara

Inhibition of in vitro ovarian cancer cell invasion by modulation of urokinase-type plasminogen activator and cathepsin B.

Hiroshi Kobayashi, Hidekazu Ohi, Motoi Sugimura et al. · PubMed · 1992 · 167 citations

Medicine, Cancer Biology, Oncology +13

Reduction of BRCA1 protein expression in Japanese sporadic breast carcinomas and its frequent loss in BRCA1-associated cases.

Kiyotsugu Yoshikawa, Kazuo Honda, T Inamoto et al. · PubMed · 1999 · 117 citations

Medicine, Molecular Biology, Oncology +15

Inhibition of metastasis of lewis lung carcinoma by a synthetic peptide within growth factor‐like domain of urokinase in the experimental and spontaneous metastasis model

Hiroshi Kobayashi, Junko Gotoh, Michio Fujie et al. · International Journal of Cancer · 1994 · 105 citations

Medicine, Oncology, Pharmacology +14

Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes

Hiroshi Kobayashi, Nobuhiko Moniwa, Motoi Sugimura et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 1993 · 98 citations

Life Sciences, Cell Biology, Molecular Biology +17

Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.

H Kobayashi, Hiromitsu Shinohara, Kinya Takeuchi et al. · PubMed · 1994 · 73 citations

Medicine, Cancer Biology, Oncology +11