CD38 is critical for social behaviour by regulating oxytocin secretion

Duo Jin, Hong-Xiang Liu, Hirokazu Hirai, +28

Nature

PsychoneuroimmunologyBehavioral SciencesBehavioral NeuroscienceAddictionOxytocin Secretion +4

Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP.

Shin Takasawa, Akira Tohgo, Naoya Noguchi, +5

Journal of Biological Chemistry

BiosynthesisBiochemistryCyclic Adp-riboseCell SignalingNatural Sciences +12

Altered Stoichiometry of FKBP12.6 Versus Ryanodine Receptor as a Cause of Abnormal Ca ²⁺ Leak Through Ryanodine Receptor in Heart Failure

Masafumi Yano, Kaoru Ono, Tomoko Ohkusa, +11

Circulation

CD38 Disruption Impairs Glucose-induced Increases in Cyclic ADP-ribose, [Ca2+] , and Insulin Secretion

Ichiro Kato, Yasuhiko Yamamoto, Miki Fujimura, +3

Journal of Biological Chemistry

Cyclic ADP-ribose Binds to FK506-binding Protein 12.6 to Release Ca2+ from Islet Microsomes

Naoya Noguchi, Shin Takasawa, Koji Nata, +5

Journal of Biological Chemistry

Pancreas TransplantationCellular PhysiologyInsulin SignalingFk506-binding Protein 12.6Molecular Pharmacology +17

Cyclic ADP-ribose and Inositol 1,4,5-Trisphosphate as Alternate Second Messengers for Intracellular Ca2+ Mobilization in Normal and Diabetic β-Cells

Shin Takasawa, Takako Akiyama, Koji Nata, +7

Journal of Biological Chemistry

Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38.

Akira Tohgo, Shin Takasawa, Naoya Noguchi, +6

Journal of Biological Chemistry

Production and Characterization of <i>Reg</i> Knockout Mice

Michiaki Unno, Koji Nata, Naoya Noguchi, +6

Diabetes

Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIIIα, RegIIIβ, RegIIIγ

Yoichi Narushima, Michiaki Unno, Kan-ichi Nakagawara, +8

Gene

Chromosomal LocalizationGeneticsMouse GenesGenetic MechanismMolecular Genetics +5

Requirement of Calmodulindependent Protein Kinase II in Cyclic ADP-ribose-mediated Intracellular Ca2+ Mobilization

Shin Takasawa, Atsuhiko Ishida, Koji Nata, +7

Journal of Biological Chemistry