Timothy Isaac Johnson

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

Marco Sciacovelli, Emanuel Gonçalves, Timothy Isaac Johnson et al. · Nature · 2016 · 584 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Fumarate induces redox-dependent senescence by modifying glutathione metabolism

Liang Zheng, Simone Cardaci, Livnat Jerby et al. · Nature Communications · 2015 · 292 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response

Daniele Biasci, Martin Smoragiewicz, Claire M. Connell et al. · Proceedings of the National Academy of Sciences · 2020 · 258 citations · Full text

Life Sciences, Immunology, Oncology +17

The ATR Inhibitor AZD6738 Synergizes with Gemcitabine <i>In Vitro</i> and <i>In Vivo</i> to Induce Pancreatic Ductal Adenocarcinoma Regression

Yann Wallez, Charles R. Dunlop, Timothy Isaac Johnson et al. · Molecular Cancer Therapeutics · 2018 · 110 citations

Medicine, Oncology, Pharmacology +17

Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models

Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson et al. · British Journal of Cancer · 2020 · 63 citations · Full text

Medicine, Oncology, Pharmacology +17