Timothy Isaac Johnson

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

Marco Sciacovelli, Emanuel Gonçalves, Timothy Isaac Johnson et al. · Nature · 2016 · 562 citations · Full text

Chromatin, Developmental Biology, Epigenetic Modifier +6

Fumarate induces redox-dependent senescence by modifying glutathione metabolism

Liang Zheng, Simone Cardaci, Livnat Jerby et al. · Nature Communications · 2015 · 287 citations · Full text

CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response

Daniele Biasci, Martin Smoragiewicz, Claire M. Connell et al. · Proceedings of the National Academy of Sciences · 2020 · 241 citations · Full text

The ATR Inhibitor AZD6738 Synergizes with Gemcitabine <i>In Vitro</i> and <i>In Vivo</i> to Induce Pancreatic Ductal Adenocarcinoma Regression

Yann Wallez, Charles R. Dunlop, Timothy Isaac Johnson et al. · Molecular Cancer Therapeutics · 2018 · 106 citations · Full text

Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models

Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson et al. · British Journal of Cancer · 2020 · 56 citations · Full text