Jeffrey L. Conroy

Using the Electrostatic Field Effect to Design a New Class of Inhibitors for Cysteine Proteases

Jeffrey L. Conroy, Tanya C. Sanders, Christopher T. Seto · Journal of the American Chemical Society · 1997 · 46 citations

Bioorganic Chemistry, Peptide Science, Chemical Biology +23

Combinatorial Library of Serine and Cysteine Protease Inhibitors That Interact with Both the S and S‘ Binding Sites

Paul Abato, Jeffrey L. Conroy, Christopher T. Seto · Journal of Medicinal Chemistry · 1999 · 30 citations · Full text

Hydrolysis of Amides Catalyzed by 4-Heterocyclohexanones: Small Molecule Mimics of Serine Proteases

Mousumi Ghosh, Jeffrey L. Conroy, Christopher T. Seto · Angewandte Chemie International Edition · 1999 · 27 citations

Engineering, Alkene Metathesis, Biochemistry +15

Demonstration by ¹³C NMR Studies That Tetrahydropyranone-Based Inhibitors Bind to Cysteine Proteases by Reversible Formation of a Hemithioketal Adduct

Jeffrey L. Conroy, Christopher T. Seto · The Journal of Organic Chemistry · 1998 · 19 citations

Pharmaceutical Science, Altmetric Attention Score, Nmr Studies +16

Synthesis of cyclohexanone-based cathepsin B inhibitors that interact with both the S and S′ binding sites

Jeffrey L. Conroy, Paul Abato, Mousumi Ghosh et al. · Tetrahedron Letters · 1998 · 13 citations

Combinatorial Chemistry, Molecular Pharmacology, Biochemistry +7