Ailong Ke

A conformational switch controls hepatitis delta virus ribozyme catalysis

Ailong Ke, Kaihong Zhou, Fang Ding et al. · Nature · 2004 · 276 citations

Virus Structure, Viral Replication, Protein Folding +5

Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System

Ki Hyun Nam, Charles H. Haitjema, Xueqi Liu et al. · Structure · 2012 · 212 citations · Full text

Rna Processing, Off-target Effect, Medicine +10

Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System

Yibei Xiao, Min Luo, Robert P. Hayes et al. · Cell · 2017 · 203 citations · Full text

Engineering, Substrate Handover Mechanisms, Structure Basis +10

Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli

Robert P. Hayes, Yibei Xiao, Fran Ding et al. · Nature · 2016 · 191 citations · Full text

E. Coli, Structural Bioinformatics, Natural Sciences +8

Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation

Yanwu Huo, Ki Hyun Nam, Fang Ding et al. · Nature Structural & Molecular Biology · 2014 · 189 citations · Full text

Chromatin, Cascade-activated Dna Unwinding, Natural Sciences +12