Craig Fraser

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach

Jason T. Weiss, John C. Dawson, Kenneth G. MacLeod et al. · Nature Communications · 2014 · 341 citations · Full text

Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine

Jason T. Weiss, John C. Dawson, Craig Fraser et al. · Journal of Medicinal Chemistry · 2014 · 197 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Bioorthogonal Chemistry +16

Rapid Discovery and Structure–Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase

Craig Fraser, John C. Dawson, Reece Dowling et al. · Journal of Medicinal Chemistry · 2016 · 69 citations · Full text

Breast Oncology, Tumor Biology, Novel Pyrazolopyrimidines +19

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability

Carolin Temps, Daniel Lietha, Emily R. Webb et al. · Cancer Research · 2021 · 50 citations · Full text

Catalytic halodefluorination of aliphatic carbon–fluorine bonds

Kelvin Kau Kiat Goh, Arup Sinha, Craig Fraser et al. · RSC Advances · 2016 · 40 citations

Chemical Engineering, Engineering, Fluorous Synthesis +8