Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative

Eva Pauwels, Neesha R. Shewakramani, Brent De Wijngaert, +8

Science Advances

SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral screening

Emiel Vanhulle, Joren Stroobants, Becky Provinciael, +4

Antiviral Research

Preprotein signature for full susceptibility to the co‐translational translocation inhibitor cyclotriazadisulfonamide

Victor Van Puyenbroeck, Eva Pauwels, Becky Provinciael, +5

Traffic

Drug TargetHucd4 SpProtein AssemblyMolecular BiologyPharmacotherapy +23

A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide

Eva Pauwels, Claudia Rutz, Becky Provinciael, +7

Molecular & Cellular Proteomics

Ribonuclease-neutralized pancreatic microsomal membranes from livestock for in vitro co-translational protein translocation

Kurt Vermeire, Susanne Allan, Becky Provinciael, +2

Analytical Biochemistry

BiochemistryBiotechnologyMembrane BiologyProtein PurificationProtein Transport +4

Intracellular Flow Cytometry Complements RT-qPCR Detection of Circulating SARS-CoV-2 Variants of Concern

Emiel Vanhulle, Becky Provinciael, Joren Stroobants, +3

BioTechniques

Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern

Emiel Vanhulle, Thomas D’huys, Becky Provinciael, +8

Frontiers in Cellular and Infection Microbiology

Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

Eva Pauwels, Becky Provinciael, Anita Camps, +2

International Journal of Molecular Sciences

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

Wolfgang Klein, Claudia Rutz, Jamina Eckhard, +9

PLoS ONE

Protein SecretionSignal RecognitionMolecular BiologySequential Screening AssayEndocytic Pathway +17

Small Molecule Cyclotriazadisulfonamide Abrogates the Upregulation of the Human Receptors CD4 and 4-1BB and Suppresses In Vitro Activation and Proliferation of T Lymphocytes

Elisa Claeys, Eva Pauwels, Stéphanie Humblet‐Baron, +5

Frontiers in Immunology