AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Matthew R. Gardner, Lisa Kattenhorn, Hema R. Kondur, +30

Nature

A Deubiquitinating Enzyme Encoded by HSV-1 Belongs to a Family of Cysteine Proteases that Is Conserved across the Family Herpesviridae

Lisa Kattenhorn, Gregory A. Korbel, Benedikt M. Kessler, +2

Molecular Cell

Viral ReplicationFamily HerpesviridaeMolecular VirologyMedicineNatural Sciences +8

Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study

Funda Meric‐Bernstam, Randy F. Sweis, Stefan Kasper, +18

Clinical Cancer Research

A Deubiquitinating Activity Is Conserved in the Large Tegument Protein of the <i>Herpesviridae</i>

Christian Schlieker, Gregory A. Korbel, Lisa Kattenhorn, +1

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyViral Structural ProteinVirus Structure +18

Identification of Proteins Associated with Murine Cytomegalovirus Virions

Lisa Kattenhorn, Ryan E. Mills, Markus Wagner, +5

Journal of Virology

Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes

Christian Schlieker, Wilhelm A. Weihofen, Evelyne Frijns, +3

Molecular Cell

Unique ClassVirus StructureViral ReplicationMolecular VirologyBiochemistry +10

Maternal CD4 ⁺ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

Kristy M. Bialas, Takayuki Tanaka, Dollnovan Tran, +19

Proceedings of the National Academy of Sciences

High-Molecular-Weight Protein (pUL48) of Human Cytomegalovirus Is a Competent Deubiquitinating Protease: Mutant Viruses Altered in Its Active-Site Cysteine or Histidine Are Viable

Jianlei Wang, Amy N. Loveland, Lisa Kattenhorn, +2

Journal of Virology

Virus StructureViral ReplicationMolecular VirologyCompetent Deubiquitinating ProteaseMedicine +13

A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation

Keith W. Jarosinski, Lisa Kattenhorn, Benedikt B. Kaufer, +2

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyPathologyMolecular BiologyHerpesvirus Usp +18

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies

Matthew R. Gardner, Ina Fetzer, Lisa Kattenhorn, +11

Molecular Therapy