Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells

Thomas Shum, Bilal Omer, Haruko Tashiro, +13

Cancer Discovery

Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1

Haruko Tashiro, Tim Sauer, Thomas Shum, +8

Molecular Therapy

HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice

Robert L. Kruse, Thomas Shum, Haruko Tashiro, +8

Cytotherapy

Viral PersistenceViral HepatitisAntiviral ActivityImmunologyHepatitis B +8

Determinants of Chest Radiography Sensitivity for COVID-19: A Multi-Institutional Study in the United States

Stephanie Stephanie, Thomas Shum, Heather Cleveland, +12

Radiology Cardiothoracic Imaging

Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors

Frank Y. Lin, Austin J. Stuckert, Candise Tat, +30

Journal of Clinical Oncology

Comprehensive Approach for Identifying the T Cell Subset Origin of CD3 and CD28 Antibody–Activated Chimeric Antigen Receptor–Modified T Cells

Michael Schmueck‐Henneresse, Bilal Omer, Thomas Shum, +9

The Journal of Immunology

A homing system targets therapeutic T cells to brain cancer

Heba Samaha, Antonella Pignata, Kristen Fousek, +24

Nature

Neuro-oncologyCell TherapyCancer ImmunosurveillanceT-regulatory CellImmunology +9

Adult and Cord Blood-Derived High-Affinity gB-CAR-T Cells Effectively React Against Human Cytomegalovirus Infections

Henning Olbrich, Sebastian J. Theobald, Constanze Slabik, +6

Human Gene Therapy

A Costimulatory CAR Improves TCR-based Cancer Immunotherapy

Bilal Omer, Mara Cardenas, Thomas Pfeiffer, +14

Cancer Immunology Research

In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy

Robert L. Kruse, Thomas Shum, Xavier Legras, +4

Molecular Therapy — Methods & Clinical Development