Kouichi Higuchi

Callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata

Motomasa Kobayashi, Kouichi Higuchi, Nobutoshi Murakami et al. · Tetrahedron Letters · 1997 · 104 citations

Biology, Marine Biotechnology, Engineering +8

Melophlins A and B, Novel Tetramic Acids Reversing the Phenotype of ras-Transformed Cells, from the Marine Sponge Melophlus sarassinorum

Shunji Aoki, Kouichi Higuchi, Ying Ye et al. · Tetrahedron · 2000 · 82 citations

Biology, Unicellular Organism, Biosynthesis +8

Novel Neuronal Nitric Oxide Synthase (nNOS) Selective Inhibitor, Aplysinopsin-Type Indole Alkaloid, from Marine Sponge Hyrtios erecta.

Shunji Aoki, Ying Ye, Kouichi Higuchi et al. · Chemical and Pharmaceutical Bulletin · 2001 · 65 citations · Full text

Molecular Pharmacology, Inhibitory Activity, Biosynthesis +14

Agosterol A, a novel polyhydroxylated sterol acetate reversing multidrug resistance from a marine sponge of Spongia sp.

Shunji Aoki, Yasuhiro Yoshioka, Yasuhisa Miyamoto et al. · Tetrahedron Letters · 1998 · 61 citations

Marine Biotechnology, Agosterol A, Sterol Acetate +4

Absolute stereostructure of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata

Nobutoshi Murakami, Wang Wei-qi, Masashi Aoki et al. · Tetrahedron Letters · 1997 · 43 citations

Biology, Marine Biotechnology, Engineering +7