Shiyang Zhai

Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment

Qingqing Guo, Huimin Zhang, Yanhong Deng et al. · European Journal of Medicinal Chemistry · 2020 · 33 citations

Protein Assembly, Biochemistry, Potential Small Molecules +12

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation

Laura Sinatra, Anja Vogelmann, F Friedrich et al. · Journal of Medicinal Chemistry · 2023 · 29 citations · Full text

Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma

Shiyang Zhai, Huimin Zhang, Rui Chen et al. · European Journal of Medicinal Chemistry · 2021 · 23 citations · Full text

Drug Targeting, Medicine, Pharmacology +11

Discovery, biological evaluation, structure–activity relationships and mechanism of action of pyrazolo[3,4-<i>b</i>]pyridin-6-one derivatives as a new class of anticancer agents

Qingqing Guo, Yao Luo, Shiyang Zhai et al. · Organic & Biomolecular Chemistry · 2019 · 19 citations