Yacine Tandjaoui-Lambiotte

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang et al. · Science · 2020 · 2.8K citations · Full text

Viral Diagnostics, Immunodeficiencies, Viral Immunity +19

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Human Loci, Disease Susceptibility, Inborn Errors +14

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki Asano, Bertrand Boisson, Fanny Onodi et al. · Science Immunology · 2021 · 410 citations · Full text

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry, Paul Bastard, Adrian Gervais et al. · Proceedings of the National Academy of Sciences · 2022 · 180 citations · Full text

Ifn Autoantibodies, Immunology, Age Dependent +16