Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer

Qiaoqi Sui, Xi Zhang, Chao Chen, +19

Nature Communications

Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer

Qiaoqi Sui, Dingxin Liu, Jiang Wu, +16

Journal for ImmunoTherapy of Cancer

Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas

Jingshu Wang, Kun Zou, Feng Xu, +17

Molecular Cancer

Neoadjuvant Immunotherapy Leads to Major Response and Low Recurrence in Localized Mismatch Repair–Deficient Colorectal Cancer

Binyi Xiao, Xuan Zhang, Taiyuan Cao, +12

Journal of the National Comprehensive Cancer Network

KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway

Changlin Zhang, Song Chen, Tianze Liu, +16

Cell Death and Disease

Kmt2a KnockdownCell RegulationMedicineMelanomaImmunology +11

Anti-PD-1-based immunotherapy as curative-intent treatment in dMMR/MSI-H rectal cancer: A multicentre cohort study

Qiaoxuan Wang, Binyi Xiao, Yong Cheng, +16

European Journal of Cancer

RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma

Tianze Liu, Wenbin Li, Wenjing Lü, +15

Theranostics

Neoadjuvant Immune Checkpoint Inhibition Improves Organ Preservation in T4bM0 Colorectal Cancer With Mismatch Repair Deficiency: A Retrospective Observational Study

Kai Han, Jinghua Tang, Leen Liao, +12

Diseases of the Colon & Rectum

Voltage-gated sodium channel Nav1.5 promotes tumor progression and enhances chemosensitivity to 5-fluorouracil in colorectal cancer

Qiaoqi Sui, Jianhong Peng, Kai Han, +14

Cancer Letters

Cancer ResearchMedicinePharmacologyTumor ProgressionColorectal Cancer +6

Efficacy of PD-1 inhibitors for colorectal cancer and polyps in Lynch syndrome patients

Jiehai Yu, Binyi Xiao, Jinghua Tang, +14

European Journal of Cancer