Aloke K. Dutta

Interaction of cocaine‐, benztropine‐, and GBR12909‐like compounds with wild‐type and mutant human dopamine transporters: molecular features that differentially determine antagonist‐binding properties

Kyle C. Schmitt, Juan Zhen, Prashant S. Kharkar et al. · Journal of Neurochemistry · 2008 · 74 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and Its Analogues as Highly Potent Dopamine D2/D3 Agonists and as Iron Chelator: In Vivo Activity Indicates Potential Application in Symptomatic and Neuroprotective Therapy for Parkinson’s Disease

Balaram Ghosh, Tamara Antonio, Maarten E. A. Reith et al. · Journal of Medicinal Chemistry · 2010 · 69 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Development of (<i>S</i>)-<i>N</i>⁶-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-<i>N</i>⁶-propyl-4,5,6,7-tetrahydrobenzo[<i>d</i>]-thiazole-2,6-diamine and Its Analogue as a D3 Receptor Preferring Agonist: Potent in Vivo Activity in Parkinson’s Disease Animal Models

Balaram Ghosh, Tamara Antonio, Juan Zhen et al. · Journal of Medicinal Chemistry · 2009 · 62 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Novel D3 dopamine receptor‐preferring agonist D‐264: Evidence of neuroprotective property in Parkinson's disease animal models induced by 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine and lactacystin

Chao Li, Swati Biswas, Xingang Li et al. · Journal of Neuroscience Research · 2010 · 57 citations

Medicine, Neuroscience, Pharmacology +17

Bioisosteric Heterocyclic Versions of 7-{[2-(4-Phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: Identification of Highly Potent and Selective Agonists for Dopamine D3 Receptor with Potent in Vivo Activity

Swati Biswas, Stuart Hazeldine, Balaram Ghosh et al. · Journal of Medicinal Chemistry · 2008 · 56 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17