Latent and active p53 are identical in conformation.

Ayeda Ayed, Frans A. A. Mulder, Gwan‐Su Yi, +3

Nature Structural Biology

Active P53Molecular BiologyConformational Study

Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia

Hu Lei, Hanzhang Xu, Huizhuang Shan, +19

Nature Communications

Homoharringtonine deregulates <i>MYC</i> transcriptional expression by directly binding NF-κB repressing factor

Xinjie Chen, Weina Zhang, Bing Chen, +16

Proceedings of the National Academy of Sciences

Binding Sites of Cytoplasmic Effectors TRAF1, 2, and 3 on CD30 and Other Members of the TNF Receptor Superfamily

Louis-Martin Boucher, Luc E. M. Marengère, Ying Lu, +2

Biochemical and Biophysical Research Communications

Signal TransductionSignaling PathwayMedicineReceptor Tyrosine KinaseImmunology +7

Targeting of AML1-ETO in t(8;21) Leukemia by Oridonin Generates a Tumor Suppressor–Like Protein

Tao Zhen, Chuanfeng Wu, Ping Liu, +15

Science Translational Medicine

Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)

Seiji Kondo, Ying Lu, Michael E. Debbas, +12

Proceedings of the National Academy of Sciences

Cancer ResearchRadiation OncologySignaling PathwayGene-targeted Mice DeficientMedicine +12

Spatiotemporal analysis of ecological vulnerability in the Tibet Autonomous Region based on a pressure-state-response-management framework

Yongjian Jiang, Bin Shi, Guijin Su, +6

Ecological Indicators

Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis

Xisheng Liu, Xiaole Meng, Xiao Peng, +10

Cell Death and Disease

Discrimination of DNA Binding Sites by Mutant p53 Proteins

Sushil K. Thukral, Ying Lu, Gregory Chad Blain, +2

Molecular and Cellular Biology

Dna RecognitionChromatinDna SequencingMolecular CharacterizationDna Binding +12

Network pharmacology-based identification for therapeutic mechanism of Ling-Gui-Zhu-Gan decoction in the metabolic syndrome induced by antipsychotic drugs

Siying Xiang, Jing Zhao, Ying Lu, +8

Computers in Biology and Medicine

Metabolic SyndromeMedicinePsychotropic MedicationPsychopharmacologyLing-gui-zhu-gan Decoction +7