Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

Nayoung Kim, Hong Kwan Kim, Kyungjong Lee, +18

Nature Communications

Metastatic Lung AdenocarcinomaImmunologyCancer BiologyTumor BiologyTumor Heterogeneity +18

Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial

Jinhyun Cho, Hae Su Kim, Bo Mi Ku, +8

Journal of Clinical Oncology

The First-week Proliferative Response of Peripheral Blood PD-1+CD8+ T Cells Predicts the Response to Anti-PD-1 Therapy in Solid Tumors

Kyung Hwan Kim, Jinhyun Cho, Bo Mi Ku, +10

Clinical Cancer Research

Caffeine-Mediated Inhibition of Calcium Release Channel Inositol 1,4,5-Trisphosphate Receptor Subtype 3 Blocks Glioblastoma Invasion and Extends Survival

Sang Soo Kang, Kyung‐Seok Han, Bo Mi Ku, +16

Cancer Research

Tumor InnervationInvasive GrowthCaffeine-mediated InhibitionCalcium SignalingMetabolic Remodeling +15

CHI3L1 (YKL‐40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells

Bo Mi Ku, Yeon Kyung Lee, Jinhyun Ryu, +14

International Journal of Cancer

PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15

Kyung Hwan Kim, Hong Kwan Kim, Hyung‐Don Kim, +12

Cellular and Molecular Immunology

MDSC subtypes and CD39 expression on CD8 ⁺ T cells predict the efficacy of anti‐PD‐1 immunotherapy in patients with advanced NSCLC

Jiae Koh, Youjin Kim, Kyoung Young Lee, +12

European Journal of Immunology

Regulatory (FoxP3+) T cells and TGF-β predict the response to anti-PD-1 immunotherapy in patients with non-small cell lung cancer

Jiae Koh, Joon Young Hur, Kyoung Young Lee, +8

Scientific Reports

Caffeine Inhibits Cell Proliferation and Regulates PKA/GSK3β Pathways in U87MG Human Glioma Cells

Bo Mi Ku, Yeon Kyung Lee, Joo Jeong, +9

Molecules and Cells

High concordance of actionable genomic alterations identified between circulating tumor DNA–based and tissue‐based next‐generation sequencing testing in advanced non–small cell lung cancer: The Korean Lung Liquid Versus Invasive Biopsy Program

Sehhoon Park, Steve Olsen, Bo Mi Ku, +8

Cancer