Hiroyasu Tsuge

Discovery of Tetrasubstituted Imidazolines as Potent and Selective Neuropeptide Y Y5 Receptor Antagonists: Reduced Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity and Potent Antiobesity Effect

Nagaaki Sato, Makoto Ando, Shiho Ishikawa et al. · Journal of Medicinal Chemistry · 2009 · 27 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Regio- and stereo-selective synthesis of trifluoromethylated isoxazolidines by 1,3-dipolar cycloaddition of 1,1,1-trifluoro-3-phenylsulfonylpropene with nitrones, and their conversion into trifluoromethylated syn-3-amino alcohols

Hiroyasu Tsuge, Takashi Okano, Shoji Eguchi · Journal of the Chemical Society Perkin Transactions 1 · 1995 · 26 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Discovery of substituted 2,4,4-triarylimidazoline derivatives as potent and selective neuropeptide Y Y5 receptor antagonists

Nagaaki Sato, Makoto Jitsuoka, Shiho Ishikawa et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Asymmetric 1,3-dipolar cycloaddition of optically active trifluoromethylated α,β-unsaturated aryl sulfones with nitrones: the use of o-dialkylaminoethyl chiral auxiliaries

Hiroyasu Tsuge, Takashi Okano, Shoji Eguchi et al. · Journal of the Chemical Society Perkin Transactions 1 · 1997 · 16 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

The synthesis of (±)-maackiain

Kenji Fukui, M. NAKAYAMA, Hiroyasu Tsuge et al. · Cellular and Molecular Life Sciences · 1968 · 14 citations

Natural Sciences, Chemistry, Medicinal Chemistry +2