Philip R. Effraim

The ribosome can discriminate the chirality of amino acids within its peptidyl-transferase center

Michael T. Englander, Joshua L. Avins, Rachel C. Fleisher et al. · Proceedings of the National Academy of Sciences · 2015 · 95 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Natural amino acids do not require their native tRNAs for efficient selection by the ribosome

Philip R. Effraim, Jiangning Wang, Michael T. Englander et al. · Nature Chemical Biology · 2009 · 41 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner

Philip R. Effraim, Jianying Huang, Angelika Lampert et al. · Neurobiology of Pain · 2019 · 37 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Na_v1.7 mutation I234T

Yang Yang, Talia Adi, Philip R. Effraim et al. · British Journal of Pharmacology · 2017 · 34 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Pharmacological characterization of a rat Nav1.7 loss-of-function model with insensitivity to pain

Lubin Chen, Philip R. Effraim, Jennifer Carrara et al. · Pain · 2020 · 29 citations

Life Sciences, Neuroscience, Pharmacology +17