Aiga Grandāne

Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases

Kaspars Tārs, Daniela Vullo, Andris Kazāks et al. · Journal of Medicinal Chemistry · 2012 · 215 citations · Full text

Tumor-associated Carbonic Anhydrases, Inhibitory Activity, Medicinal Chemistry +13

6-Substituted Sulfocoumarins Are Selective Carbonic Anhdydrase IX and XII Inhibitors with Significant Cytotoxicity against Colorectal Cancer Cells

Aiga Grandāne, Muhammet Tanç, Lorenzo Di Cesare Mannelli et al. · Journal of Medicinal Chemistry · 2015 · 96 citations · Full text

6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII

Aiga Grandāne, Muhammet Tanç, Raivis Žalubovskis et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 69 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9

Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII

Aiga Grandāne, Muhammet Tanç, Raivis Žalubovskis et al. · Bioorganic & Medicinal Chemistry · 2014 · 55 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, 6-Tetrazolyl-substituted Sulfocoumarins +8

Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action

Aiga Grandāne, Muhammet Tanç, Raivis Žalubovskis et al. · Bioorganic & Medicinal Chemistry · 2015 · 45 citations · Full text

Medicinal Chemistry, Derivative (Chemistry), Biochemistry +6