Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

Thomas Lindenstrøm, Else Marie Agger, Karen Smith Korsholm, +5

The Journal of Immunology

VaccinationAllergyMedicineT-regulatory CellMycobacterium Tuberculosis +12

Genotoxicity, cytotoxicity, and reactive oxygen species induced by single‐walled carbon nanotubes and C₆₀ fullerenes in the FE1‐Muta™Mouse lung epithelial cells

Nicklas Raun Jacobsen, Giulio Pojana, Paul A. White, +7

Environmental and Molecular Mutagenesis

EngineeringLung InflammationSwcnt ExposureCell DeathNanotoxicology +18

Safety and immunogenicity of the chlamydia vaccine candidate CTH522 adjuvanted with CAF01 liposomes or aluminium hydroxide: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial

Sonya Abraham, Helene Bæk Juel, Peter Fibiger Bang, +16

The Lancet Infectious Diseases

VaccinationMucosal VaccinationCaf01 LiposomesImmunologyAluminium Hydroxide +2

The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes

Karen Smith Korsholm, Else Marie Agger, Camilla Foged, +5

Immunology

Combination of the Cationic Surfactant Dimethyl Dioctadecyl Ammonium Bromide and Synthetic Mycobacterial Cord Factor as an Efficient Adjuvant for Tuberculosis Subunit Vaccines

Lars Holten-Andersen, T. Mark Doherty, Karen Smith Korsholm, +1

Infection and Immunity

Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31

Else Marie Agger, Ida Rosenkrands, Anja Weinreich Olsen, +8

Vaccine

VaccinationImmunologyAutoimmunityHumoral ImmunityImmunomodulation +5

T‐helper 1 and T‐helper 2 adjuvants induce distinct differences in the magnitude, quality and kinetics of the early inflammatory response at the site of injection

Karen Smith Korsholm, Rune V. Petersen, Else Marie Agger, +1

Immunology

A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

Dennis Christensen, Malou Henriksen‐Lacey, Arun T. Kamath, +9

Journal of Controlled Release

VaccinationVaccine DevelopmentAllergyUnsaturated AnalogMedicine +10

Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

Karen Smith Korsholm, Jon Hansen, Kasper K. Karlsen, +6

Vaccine

Cd8+ T-cell ResponsesSubunit AntigensT-regulatory CellImmunologyAntigen Processing +7

Cationic Liposomes Containing Mycobacterial Lipids: a New Powerful Th1 Adjuvant System

Ida Rosenkrands, Else Marie Agger, Anja Weinreich Olsen, +4

Infection and Immunity

Proteinlipid InteractionHumoral ResponseImmunologyInnate Immune SystemInnate Immunity +17