Glycosaminoglycan and proteoglycan inhibit the depolymerization of β2-microglobulin amyloid fibrils in vitro

Itaru Yamaguchi, Hironori Suda, Naoki Tsuzuike, +8

Kidney International

BiochemistryGlycobiologyProtein MisfoldingPolysaccharideProteoglycan Inhibit +4

Inhibitory Effect of β-Alanyl-L-Histidinato Zinc on Bone Resorption in Tissue Culture

Masayoshi Yamaguchi, Yoshihide Segaw, Noriaki Shimokawa, +2

Pharmacology

Bone ResorptionBiochemistryMedicinePhysiologyAhz Effect +13

Important Role of Peptide Leukotrienes (p-LTs) in the Resting Tonus of Isolated Human Bronchi

Shigekatsu Kohno, Naoki Tsuzuike, Hideki Yamamura, +3

The Japanese Journal of Pharmacology

Methotrexate suppresses nitric oxide production ex vivo in macrophages from rats with adjuvant-induced arthritis

Takeshi Omata, Y. Segawa, Naonori Inoue, +3

Research in Experimental Medicine

InflammationRheumatologyRheumatoid DisorderAnti-inflammatoryAutoimmune Disease +10

Changes in urinary deoxypyridinoline level and vertebral bone mass in the development of adjuvant-induced arthritis in rats

Y. Segawa, Toshitaka Nakamura, Shigeo Aota, +4

Bone

MechanobiologyRheumatologyBone DiseaseMedicinePhysiology +11

β-Alanyl-L-histidinato zinc prevents hydrocortisone-induced disorder of bone metabolism in rats

Y. Segawa, Naoki Tsuzuike, Yoshihiko Itokazu, +2

Research in Experimental Medicine

Bone DiseaseMedicinePhysiologyBone HomeostasisMetabolic Bone Disease +5

Expression of Cytokine mRNA in Extrahepatic Organs in a Mouse Concanavalin A-Hepatitis Model

Toshihiro Okamoto, Yoshihisa Nakano, Wataru Asakura, +3

The Japanese Journal of Pharmacology

ImmunologyImmune RegulationPathologyImmunologic MechanismCon A +22

Preventive Effect of .BETA.-Alanyl-L-histidinato Zinc on the Deterioration of Bone Metabolism in Ovariectomized Rats.

Y. Segawa, Naoki Tsuzuike, E Tagashira

Biological and Pharmaceutical Bulletin

Preventive EffectBone HealthBeta-alanyl-l-histidinato ZincMedicinePhysiology +12

Important roles of tachykinins in the development of allergic nasal hyperresponsiveness in guinea‐pigs

Takeshi Nabe, Naoki Tsuzuike, Yasuyoshi Ohtani, +6

Clinical & Experimental Allergy

Effects of ZNC-2381, a New Oral Compound, on Several Hepatic Injury Models and on Hepatocellular Apoptosis in Mice and Rats

Yoshihiko Itokazu, Yoshihide Segawa, Takeshi Omata, +7

Journal of Pharmacy and Pharmacology

PathologyCell DeathPharmacotherapyToxicological MechanismOxidative Stress +17